Kudzu Extract May Help Control Alcohol Cravings
Keung et al. reported that Daidzin is a potent, selective, and reversible inhibitor of human mitochondrial aldehyde dehydrogenase and this natural compound suppresses free-choice ethanol intake by Syrian golden hamsters. The anti-craving effect of disulfiram may also be due to inhibition of dopamine beta hydroxylase thereby increasing neuronal dopamine . A growing number of double-blind, peer reviewed studies have confirmed the effectiveness of using kudzu for alcoholism.
- Lukas and Lee hold a patent for kudzu extract to treat alcohol abuse and dependence.
- My standards for categorizing an herb or drug as a “miracle” supplement are quite high.
- We’re separating fact from fiction on this homeopathic remedy.
- In its native China, kudzu has long been used to help people control their desire for alcohol.
The active ingredients are all encapsulated, or enveloped, using specific processing techniques, within phosphatidyl choline based spheres that act as transport vehicles. The process mimics natural actions that take place within the gut to enable proper absorption of nutrients, especially phyto-nutrients and fat soluble vitamins. The body’s own process in this regard creates micelles, single layer or unilamellar spheres in the size range of approximately 100 nanometers that typically can transport single nutrients.
Can Alcohol Deplete The Body Of Nutrients?
Since kudzu root reduces the amount of alcohol consumed it may be effective as hangover prevention. However, kudzu root is not effective as a hangover cure when taken the morning after drinking. McGregor cautions that taking kudzu root the morning after may actually have long term negative medical effects. Kudzu flower appears to help eliminate acetaldehyde in humans, but the effectiveness of kudzu flower as a hangover remedy has yet to be confirmed in a placebo controlled double blind study. Even though kudzu root appears to have a mechanism similar to antabuse in that it allows acetaldehyde to accumulate in the body–kudzu root is a very gentle medication with none of the violent effects of antabuse.
Recently, unique discoveries have been made pertaining to the actions of bitters, and a family of 30 specific bitter flavor receptors in the GI Tract. Known as TAS2R’s, these receptors are located throughout the gut and are set to detect a variety of differing bitter profiles. Throughout the gut and endocrine system, digestive secretions are promoted in the stomach, pancreas, gall bladder, liver, and small and large intestine. Bitters have been used to help relief symptoms of constipation, flatulence, appetite loss, vomiting, heartburn, abdominal pain and nausea . They are also interested in the possibility of developing a dosage of kudzu that individuals could take once, before a night of drinking, rather than a set of pills which must be taken regularly. Get FREE daily coaching messages from Chris Scott to help you quit or cut down on alcohol in just 10 days. In my opinion, the Planetary Herbals brand is a great option for someone who has not yet quit drinking, and who wants to try pure kudzu powder on its own.
Kudzu Vine Extract For Alcohol Treatment: The Study
The kudzu plant is a vine that resembles poison ivy and is native to several Asian countries. Small studies in people have observed noteworthy improvements in these menopausal symptoms, among others, like vaginal dryness . You can eat the root as you would other root vegetables, like potatoes or rutabagas. Kudzu roots can be dried and ground into a powder, which some people use as breading for fried foods or as a thickener for soups and sauces. Kudzu root, also called Japanese arrowroot, is native to China, Japan, and Korea. Today, kudzu grows in other parts of the world as well, including in the southern United States.
Kudzu Root c/s from Queen of Trees Herbal. Alcohol Cravings, shoulder pain with flu, fever, hypertension… http://t.co/v74XdM2c
— Public Inbox (@publicinbox) June 18, 2012
After completion of the program each subject re-took the AUD questionnaire and also filled out an exit interview. The Declinol Compound for the study was manufactured according to cGMP guidelines and was processed how to reduce alcohol cravings naturally at an FDA registered, OTC, Rx facility. The current evidence favors the safety of Kudzu root although some have questioned the potential build- up of acetaldehyde following its administration to humans .
While we only selected a small number of patients to study in this pilot because we wanted to capture a positive effect prior to a much larger study being planned in the future, we are encouraged with these preliminary results. Importantly, 40% of these patients relapsed more than five times indicating serious problems with alcohol abuse/dependence. Certainly we caution any real interpretation which must await further study. This lack of bitter flavor ingestion compromises not only overall health, but may allow for a greater risk of alcohol intake. The bitter compounds contained in Declinol can promote better health overall, while also helping to better ensure that the TAS2R receptors in the human gut are stimulated adequately. There’s some evidence that acupuncture, mindfulness, and meditation help during AUD treatment.
Herbal Treatment Helps Curb Urge To Drink
Individuals taking naltrexone can still drink and become intoxicated, but they will not experience the pleasure and reward that alcohol provides, thus disincentivizing the consumption of alcohol. Kudzu root has been known for centuries in Traditional Chinese Medicine as ge-gen. The first written mention of the plant as a medicine is in the ancient herbal text of Shen Nong (circa A.D. 100). The historical application for drunkenness has become a major focal point of modern research on kudzu. It is also used in modern Chinese medicine as a treatment for angina pectoris. Kudzu extract is a herbal remedy that may help minimize alcohol cravings and reduce heavy drinking episodes.
McLean Hospital has licensed the production of kudzu extract (NPI-031) to Natural Pharmacia International , Inc. that markets it as Alkontrol-Herbal™. Excessive alcohol consumption is a leading cause of illness worldwide (Shield et al., 2013) and has a significant impact on the health of millions people. The impact of excessive alcohol consumption results in increased healthcare costs, loss of productivity, alcohol-related crime , and motor vehicle accidents. Naturopathic physician Maura Henninger notes in an article on Huffington Post that B vitamins are essential in breaking addictions to both alcohol and drugs. According to Henninger, thaimine — vitamin B-1 — is particularly important to supplement, as it helps reduce fatigue and brain fog.
Addiction & Recovery
Protective effect of puerarin against burn-induced heart injury in rats. Other research suggests that kudzu supplements may also play a role in preventing migraine attacks. These are exciting findings, but much more research is needed before we can be sure. Kudzu root, leaf, and flowers have been used in Traditional Chinese Medicine for centuries. But today you can find it in the supplement aisle of most grocery stores. Your call is confidential, and there’s no pressure to commit to treatment until you’re ready. As a voluntary facility, we’re here to help you heal — on your terms.
Kudzu can be purchased with ease online and it won’t break the bank. However, there are a lot of supplements that claim to contain kudzu that are mostly cheap fillers. Kudzu is known to be extremely safe, with very few reported adverse side effects. In terms of what I felt when I took kudzu, my experience supports the observations of others who note that kudzu might act like a much gentler form of disulfiram or Antabuse. These drugs are often prescribed to alcoholics to keep them abstinent. Even a tiny amount of alcohol can cause violent illness while on these drugs. By contrast, kudzu creates a mild flushed feeling at most and leaves the drinker craving alcohol a bit less.
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Kudzu root can also be a natural option to treat inflammation. In a small case study, researchers found that isoorientin, a compound isolated from kudzu root, is capable of boosting antioxidant levels and reducing inflammation in mice with swollen paws. Other supplements such as L-glutamine and milk thistle are thought to decrease cravings and aid in detoxifying the liver, respectively. There is some evidence that milk thistle aids in the regeneration of liver cells. However, these supplements have not been thoroughly substantiated with scientific research to confirm the efficacy of their actions and benefits.
This herb should be avoided by alcoholics, however, because it too has the potential to cause severe liver damage. Many other supplements can potentially be toxic to the liver, an organ already compromised by alcoholism, which is why it is important to first consult with a doctor before taking any supplements for alcohol cravings. “Recently, preclinical studies with animals have shown reductions in alcohol consumption when treated with isoflavones contained in the kudzu root,” said Penetar. “Therefore, the next step in the research was to assess the effects of kudzu extract on different physical, behavioral and cognitive features in humans.”
Vitamins & Supplements
“Without a doubt, kudzu is here to stay. Although landowners can get effective kudzu control, eradication from the United States is not currently feasible.” A. Several studies have indicated that even recommended amounts of vitamin A might weaken bones and lead to fractures. But Sober living houses new research suggests that normal doses of beta carotene and vitamin A are not related to fracture risk. Many people have reported success soaking infected nails in 1 part vinegar to 2 parts water. Such remedies won’t work for everyone and take several months to produce results.
We are cognizant that alcohol abuse induces severe effects on brain reward circuitry affecting stress/anxiety as well as reticular formation in the brain. These problems may have to be addressed in future studies and may require additional therapies and neurochemical epigenetic modifications. This is the first ever pilot results showing that the complex Declinol, significantly reduced Alcohol Use Disorders Identification Test scores in moderate to heavy drinkers in a naturalistic setting (Figure 1 and 2; Table 3). While this is a small pilot study requiring additional large scale controlled studies, we are encouraged. To our knowledge the present pilot is the first such a study in the world that has systematically evaluated this novel complex in humans. Purified puerarin another ingredient in Kudzu root was also shown to suppress alcohol intake in the short term as well reducing withdrawal reactions in high ethanol preferring rats. However this effect does not seem to be due a central brain mechanism .
May Ease Menopause Symptoms
The isoflavone glucoside conjugates are easily altered during extraction, processing, and cooking. However, the total concentration of isoflavones does not change.
Franke et al. found that both post- and premenopausal women may begin to produce equol with increased isoflavone exposure. Daidzein and glycitein in soy and kudzu, and formononetin and biochanin A in red clover. Is one of the earliest medicinal plants used in traditional Chinese medicine. It has many profound pharmacological actions, including antidipsotropic activity. In Chinese pharmacy books, kudzu is listed as a possible treatment for alcohol-related hangovers and cravings, Penetar tells WebMD. About 1 in 6 U.S. adults binge drinks, according to a CDC report.
But kudzu doesn’t seem to decrease the craving for alcohol or improve sobriety in long-term alcoholics. In the 1980s, animal studies showed that naltrexone also reduced alcohol consumption. Human clinical trials were performed in the late 80s and early 90s. These trials showed that naltrexone could decrease alcohol cravings and relapse risk when combined with psychosocial therapy. Ivan Diamond is an alcoholism researcher at the University of California, San Francisco. The researchers observed 12 men and women in a double-blind placebo-controlled study.